John Charles Farley, 51, was charged with murder in the death of Stephanie Farley.
Authorities said police went to the Farley home on Hampton Chase Court on Sept. 30 after paramedics reported Stephanie Farley suffered a suspicious injury. She died of her injuries on Oct. 14.
Neighbors said police have been called to the home several times in the past.
Court records showed there is a history of domestic violence with the couple, but Stephanie Farley was the one who has been charged in the past. She was arrested three times in the last year on charges of assaulting her husband.
According to arrest warrants, she struck, scratched and bit her husband. During one incident, she stabbed him with a pen and threatened to kill him.
John Farley had never been in trouble with the law before, according to his court attorney, Seth Blum.
"I believe there will be witnesses who will come forward and say the sort of injuries that were described are not surprising, given what they have seen in manic episodes in the past," said Blum.
During John Farley's initial court appearance, prosecutors asked that he have no contact with his 12-year-old daughter and 15-year-old son, who were at home when their mother was injured.
John Farley's attorney asked that he be set free on bond.
"They have lost their mother, we would contest through an accident. She had significant mental health issues that resulted in a number of manic episodes that resulted in a number of arrests," Blum said during the hearing.
Farley was being held without bond in the Wake County jail.
His next court appearance is Nov. 17.