Alan Thompson, 30, of Greenville, was driving a Toyota west on N.C. Highway 42 near Pinetops when he traveled left of center and struck a 2011 Mazda driven by Randy Collins, 53, of Elm City, at about noon, the North Carolina State Highway Patrol said.
Thompson and two of his passengers – Mickeyla Little, 15, and Christian Thompson, 2, both of Greenville – died. One person in the Mazda was killed - Stephanie Collins, 45, of Elm City.
Randy Collins was taken to Vidant Medical Center in Greenville in stable condition.
Little was a cheerleader who lived hip-hop dance, said her mother, Zena Thompson.
Investigators believe speed was a factor in the wreck.