Carl Anthony Presley, 35, was killed around 2:30 a.m. inside his apartment at 3307 Mordecai St., police said.
Arrest warrants were issued Tuesday night for Kerry W. Graham Jr., 16, of 1315 Morreene Road, on charges of first-degree murder and first-degree burglary, police said.
Graham is not in custody.
Anyone with information on his whereabouts is asked to call Durham police at 919-560-4440, extension 29320 or Crime Stoppers at 919-683-1200. Crime Stoppers pays cash rewards for anonymous tips that solve crimes.
The apartment complex is near Duke University, but police said no students were involved.