Sachin Sunil Kapoor, 24, is believed to be suffering from dementia or some other cognitive impairment.
Kapoor was last seen at the Cary Public Library, at 310 S. Academy St., and could be headed toward Greensboro, officials said.
He is described as white, about 5 feet, 8 inches tall and 165 pounds. He is bald, having shaved his head recently, and has brown eyes.
Anyone with information on his whereabouts is asked to call the Cary Police Department at 919-469-4012.
Developed in 2007, Silver Alert is a system to quickly notify the public about missing endangered adults who suffer from dementia or other cognitive impairments, such as Alzheimer's disease.
It also allows caregivers and nursing homes to report a person missing. In the past, only a family member could report an adult missing.