Name: Researcher says vaccine patch is more effective, easier to administer than shot
Uploaded: 2021-09-24T19:28:42-0400
Duration: 245076
Description: Joseph DeSimone, a Stanford University chemistry professor who for years held a dual appointment at UNC-Chapel Hill and N.C. State University, discusses his research into a vaccine patch.

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Joseph DeSimone, a Stanford University chemistry professor who for years held a dual appointment at UNC-Chapel Hill and N.C. State University, discusses his research into a vaccine patch.

>> WOW, MARK, THANK YOU. >>> WELL A REALLY COOL STORY FROM WRAL'S BRYAN MIMS. IF YOU MISSED IT IN OUR LAST HOUR, A VACCINATION WITHOUT THE SHOT. LOCAL RESEARCHERS HAVE DONE IT AGAIN PROVING THEY'RE AMONG THE BEST OF THE BEST. YOU'RE LOOKING AT A 3-D PRINTED VACCINE PATCH, WHICH OFFERS A VACCINATION WITHOUT A SHOT. AND TO MAKE THIS EVEN MORE IMPRESSIVE. EARLY RESEARCH SHOWS IT OUTPERFORMS NEEDLE JABS WHEN IT COMES TO BOOSTING IMMUNITY. >> LEADING THE RESEARCH COLLABORATION BETWEEN STANFORD AND UNC-CHAPELL HILL. HE JOINS US LIVE TONIGHT. PROFESSOR, FIRST OF ALL THANKS FOR BEING WITH US. WE WANT TO START BY ASKING YOU WHAT PROMPTED THE IDEA FOR THIS PATCH? WAS THIS SOMETHING ALREADY IN THE WORKS BEFORE COVID? >> IT WAS. THANK YOU FOR THE INTEREST IN THE WORK. SO YES, WE'VE BEEN WORKING ON NEW APPROACHES FOR LOCAL DRUG DELIVERY FOR SOME TIME NOW. IT'S REALLY LEVERAGING BREAKTHROUGHS IN FABRICATION. IN THIS PARTICULAR CASE 3-D PRINTING THAT ALLOWS ONE TO MAKE THINGS YOU CAN'T MAKE ANY OTHER WAY. LOCAL DRUG DELIVERIES IS IMPORTANT BECAUSE THE VACCINE IS TARGETING IMMUNE CELLS. IT'S QUITE CLEAR WE HAVE 100,000 MORE IMMUNE CELLS IN OUR SKIN THAN WE DO IN OUR MUSCLE. AND THE NORMAL INJECTION IS ACTUALLY MISSING THE MAJORITY OF THOSE CELLS, SO BY HAVING A LOCAL DELIVERY, WE GET THIS ENHANCEMENT GOING FORWARD. >> JOE, I LOOKED IT UP. YOU AND I HAVE BEEN TALKING ABOUT NANO TECHNOLOGY FOR 23 YEARS. NOT TO AGE EITHER OF US, BUT YOU'VE BEEN AT THIS FOR A LONG TIME. TALK ABOUT THIS RESEARCH AND HOW THIS COMPARES TO A TRADITIONAL VACCINE. >> YEAH, WE'VE BEEN AT THIS FOR A WHILE. BUT THE ADVANTAGE OF A SOLID STATE APPROACH FOR DELIVERY IS NOT ONLY A LOCAL DELIVERY, WHICH WE GET THIS INCREASE IN PERFORMANCE, BUT WE ARE NO LONGER USING LIQUIDS. THE VACCINE MOLECULES ARE ACTUALLY IN A COATING ON THESE NEEDLE LES IN THE FLORIDA SUGAR SOLUTION. SO THEY'RE ACTUALLY WRAPPED AND BATHED IN A SOLID STATE OF SUGAR, WHICH DISSOLVES VERY QUICKLY. BEING IN A SOLID STATE SHOULD ALLOW THESE VACCINES TO AVOID AND MITIGATE THE COLD CHAIN FOR THE VACCINE, BUT HAVING A SOLID STATE FORMULATION COULD MITT GAME THAT AND PLUS WITH HOW TO HELP THOSE HEALTHCARE WORKERS AND PAIN FREE AND ANXIETY FREE. THIS SHOULD BE PRETTY IMPACTFUL. >> YOU MAY NOT HAVE FIGURED THIS OUT YET, BUT HOW WILL YOU ADHERE TO THE BODY? HOW LONG WILL A PERSON HAVE TO WEAR THIS? >> SO WE'RE THINKING IT'S GOING TO LOOK LIKE A BAND-AID. IT'S GOING TO BE WORN FOR ABOUT TWO HOURS. AND THAT IS PLENTY OF TIME FOR THESE COATINGS TO DISSOLVE IN THE SKIN. >> WHAT ARE THE NEXT STEPS IN THIS PROCESS? IS THIS SOMETHING WE CAN SEE ON THE MARKET ANY TIME SEASON? >> YES, SO THE FPA HAS A TRIED AND TRUE ACCOUNT. WE'RE EXPECTING TO BE IN NON-HUMAN PRIMATES IN THE FIRST HALF OF 2022. THE DATA WILL TAKE ABOUT SIX MONTHS, BUT WE ARE TALKING TO ALL THE INDUSTRIAL PLAYERS IN THIS SPACE AND THEY ALL BELIEVE THAT, YOU KNOW, TIME HAS COME WHERE YOU REALLY NEED TO PIVOT AWAY FROM SYRINGES AND NEEDLES AND LIQUID FORMULATIONS FOR VACCINES AND MOVE TO PATCHES THAT COULD ARRIVE BY AMAZON OR THE POST SERVICE AND BE SELF-ADMINISTERED. WE'VE GOT A LOT OF PARTNERSHIPS EMERGING. >> WE'RE LOOKING AT A COUPLE OF YEARS BEFORE YOU SEE THIS, BEING ABLE TO APPLY IT TO HUMAN BEINGS. BUT TRULY FASCINATING RESEARCH. WE WISH YOU ALL THE BEST. >> THANK YOU. I THINK THAT'S A REASONABLE TIME FRAME. >> ALL RIGHT, THANK YOU SO

Debra Morgan

Gerald Owens

Matthew Burns

Researcher says vaccine patch is more effective, easier to administer than shot

Joe DeSimone, former UNC/NCSU professor

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I'm meteorologist, Kat Campbell in the wr a severe weather center, a turbulent week ahead with more storm threats on the horizon, severe weather threats, a level two risk Wednesday and Thursday because of that these days and nicer wr weather alert days. If we take a look at our cold front, it's still well to the west. But as it gets closer to us, we're going to have more forcing for storms to develop and a ripe atmosphere for those storms to intensify, damaging wind gusts and hail are the main concerns though an isolated tornado will be possible. Storms most likely Wednesday night overnight into early Thursday and there could be another chance later Thursday, depending on how that Wednesday night round evolved. So let's first talk about the Wednesday a few hit or miss storms possible pretty much anywhere during the afternoon, but the main, so look like it would come overnight. So we're talking past midnight, likely through very early Thursday morning, 234, 5 a.m. And then the second round approaches from the west and depending on how that first round goes, that's going to determine the strength and the timing of the second round. This model in particular has a moving through a bit early in the day. We'll watch to see if that trend holds. Keep checking in for updates as we get closer to Thursday for Wednesday. It's hot, high temperatures in the upper eighties to lower nineties just isolated storm chances during the day. But that chance, of course, going up later at night, if we look at how hot it's been this spring, it's pretty remarkable. It feels more like summer than spring and it is the warmest spring to date on record at RDU. Temperatures are running 4.7 degrees normal, almost five degrees above normal. We do have a cold front coming and some below normal temperatures briefly return at the forecast Friday, 78. Still some scattered storms around Saturday. We dry out to start the weekend, 75 of the high and near 80 on Mother's Day. Mother's Day is trending drier on Sunday with more sunshine. And you, I notice the cooler weather this weekend when you get to the nighttime hours early in the morning lows dip back in the fifties. A much drier, less humid air returns for the weekend. That should last until early next week. But we still have to get through the turbulent weather first. The worst of it comes Wednesday and Thursday, Friday still some scattered storms. But at this point, those are less likely to be severe.

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Good evening. I'm Tina Soldan Cash with the night time lottery drawing for Tuesday. May 7th, 2024. 1st winning pick three tonight is seven, followed by eight, third pick three is six and our pick three. Fireball number is eight. Joining me for tonight's drawing is our auditor from mcconn Jones L LP. Now it's time for the Carolina pick four, check your tickets. Good luck. Eight is our first winning pick four followed by six, third pick for tonight. Another six fourth winning number is zero and our pick for a fireball number tonight is three. Let's turn now to the Carolina cash five. If no one matches all five numbers to win the jackpot tonight, tomorrow's top prize is an estimated $493,000. Good luck. Six is our first winning cash five number tonight followed by seven. Third winning number is 19. Our fourth cash five tonight 11 and our final winning number is 15. The North Carolina education lottery has contributed over $10 billion to education. Thanks for your support and get the winning numbers right here every night. Thanks for playing

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>> ACROSS AMERICA WITH MEGA JACKPOTS, IT'S MEGA MILLIONS AMERICA ON TIME. CODE IS TUESDAY MAY 7TH AND TONIGHT'S MEGA MILLIONS JACKPOT IS AN ESTIMATED A NEW TIES 306 MILLION DOLLARS DOING THAT JACKPOT. YOU MUST MATCH THESE 5 WHITE. PLUS THAT GOLD MEGA MALL. NOW, LET'S SEE IF I CAN MAKE YOU A MILLIONAIRE TONIGHT. OUR FIRST WINNING NUMBER TONIGHT IS 63 FOLLOWED BY 28. UP NEXT, WE HAVE 36 YOU NEXT NUMBER IS 66 IN YOUR FINAL WHITE BALL NUMBER FOR THIS EVENING IS 26 NOW FOR THE MEGA BALL NUMBER THAT IS 15 AGAIN. TONIGHT'S WINNING NUMBERS ARE 63. 28. 36 66. 26 IN THE GOLD.

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Wake County Public School System Superintendent Robert Taylor and Wake County School Board members discussed the county's budget proposal for the district for the 2025 fiscal year. The meeting comes one day after Wake County Commissioners proposed a $49 million increase in funding for the next fiscal year.

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Daytime Pick 3 and Pick 4 drawings are held at 3 p.m. daily. They can be seen as live or on-demand video.

Hey there. Good afternoon. I'm Noah Klein. Welcome to this afternoon's draws for Tuesday, May 7th 2024. Let's get it going here with Carolina pick three. That first pick three number is seven. Second number is zero third, number two, pick 35. Roll number is seven. Joining me for this afternoon draws our auditor from mcconnell and Jones L LP. Now let's move to the Carolina pick four. That first pick four number is seven. Second number six, eight. Fourth number is nine and our pick for a firewall number is five. The North Carolina Education lottery contributed over $10 billion education. Thank you for your support. Get your winning numbers each day at 3 p.m. and again at 11:22 p.m. right here on your exclusive station for the North Carolina Education Lottery.

Daytime Pick 3 and Pick 4 Drawing

President Joe Biden is expected to condemn antisemitism during a Tuesday ceremony to remember victims of the Holocaust at a time when the Hamas attack on Israel and controversy over the war in Gaza have sparked new waves of violence and hateful rhetoric toward Jews.

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Researcher says vaccine patch is more effective, easier to administer than shot

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