Investigators said Bonnie Gay Brooks, 49, did not return to her home on Monday evening.
Officers said they are concerned about Brooks, because they don't believe she has her medication with her. No foul play is suspected in her disappearance.
Brooks was described as a white woman standing 5 feet 4 inches tall. She has brown hair and green eyes.
Brooks drives a silver 2006 Hyundai sedan with the N.C. license plate number WPN-2372.
Anyone with information on Brooks' whereabouts was asked to call Raleigh police at 919-890-3555.
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