Investigators said Andrew William Kraft II, of Raleigh, was drunk when he rear-ended another car on the Interstate 440 Beltline, veered off the highway and went down a hill by an overpass.
He crossed six lanes of South Saunders Street, officials said.
Crews had to cut Kraft out of the car. He was in critical condition at WakeMed.
Investigators charged Kraft with driving while impaired, careless and reckless driving and driving with a revoked license. More charges were possible, police said.