Many of them who worked years to get their businesses established are starting all over again.
An Eckerd Drug Store in Goldsboro is getting back on its feet. Workers are still tearing water-damaged pieces out of the destroyed building, but that has not stopped store owners from opening their doors to the public.
In the parking lot, a trailer connected to a generator serves as a make-shift pharmacy and drug store. Owners say they hope to be back into a new store by January.
Still, customers are finding just about everything they need inside the makeshift drug store -- everything from diapers to aspirin to prescriptions from the pharmacy.
"We've only been open for business for about three days now," says store supervisor Sheila Mattey. "And so most of the kinks are out, and we're able to accommodate our customers well, and for the most part, things are running very smoothly."
This one little trailer is a little miracle for Linda Lane. "It's a blessing," she says.
"We love our customers," says Mattey. "It's a great community. They have enough to worry about without having to worry about their prescriptions and having to go somewhere else for them. We're just trying to make it easy for them."
The water mark stands at three feet in Ralph Weaver's tire store. Now he is ten feet deep in rotted wood. His office is gutted, but he is back selling tires.
"I have no problem," Weaver says. "Just get the water out of them, and you're ready to go."
To get through the disaster, Weaver says he is counting on a loan from the bank he has dealt with for years. Other business owners are counting on loans from the SBA and from FEMA to help them.