After a 12-hour bus ride to Ohio, the Bulls left 14 on base in the loss to the Mud Hens.
Toledo is an International League best 7-1, while Durham is still tied for the lead in the Southern Division, despite a 4-5 record.
Toledo's first baseman Mike Hessman took away an extra-base hit from Durham's Steve Cox in the opening inning, a line drive that probably would have scored two runs. The Mud Hens then scored twice in the first, and never trailed.
Toledo took advantage of three B.J. Upton errors to score four unearned runs, as Jim Magrane (0-1) took the loss. Damon Hollins had three hits and Paul Hoover two doubles one day after his 29th birthday to lead Durham.
Jason Roach (1-0) will try to get the Bulls on track on Saturday against John Ennis at 7 p.m. Airtime on WDNC 620 AM is at 6:30 p.m.
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