Sandra Odom is charged with involuntary manslaughter and misdemeanor child abuse in the death of her stepson Jarrett Odom.
Investigators said Odom left Jarrett and his twin brother, Garrett, alone in a backyard pool July 5, 2001. Garrett survived and is now in the custody of his biological mother.
Odom's first trial in January ended in a mistrial.
Odom's lawyers said Jarrett suffered from a genetic disorder called water intoxication. Water intoxication causes a condition called hyponatremia, which means not having enough sodium in the blood. Odom's lawyers are expected to have an expert testify about water intoxication in this case.
The information about water intoxication did not come out in the first trial.
Opening statements are expected Tuesday morning.
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