Deron C. Wiley, 28, of Burlington, was shot once in the left side outside 778 Sports Club at 778 S. Graham Hopedale Road around 2:20 a.m., police said. He was taken to UNC Hospitals in Chapel Hill.
Police said more than 200 people were at the club, and officers had to call in other departments to help with crowd control.
Investigators have not identified a suspect.
Anyone with information about the shooting is asked to call Burlington police at 336-229-3500 or Crime Stoppers at 336-229-7100. Crime Stoppers pays cash rewards for anonymous tips that solve crimes.