Name: Experimental COVID-19 drug could be given orally, meaning it would be easier for more people to take
Uploaded: 2021-02-09T20:05:51-0500
Duration: 146188
Description: UNC-Chapel Hill researcher Lisa Gralinski discusses an experimental oral drug that has shown potential to both prevent and treat COVID-19.

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UNC-Chapel Hill researcher Lisa Gralinski discusses an experimental oral drug that has shown potential to both prevent and treat COVID-19.

EXPECTED TO RECEIVE 100 DOSES. 313 STORES ARE EXPECTED TO ADMINISTER THEM IN NORTH CAROLINA. >>> WHILE MANY VACCINES ARE A GREAT THING, WE CAN'T FORGET ABOUT TREATMENTS. RESEARCHERS AT UNC ARE INSTRUMENTAL AND THAT DEVELOPMENT, REMEMBER REMDESIVIR, THEY DID NOT STOP THERE, NOT BY ANY MEANS. TONIGHT WE LEARNED AN EXPERIMENTAL DRUG SHOWS PROMISING SIGNS OF BOTH PREVENTING AND TREATING COVID. DR. LISA GURINSKI IS WITH US. ON THE RESEARCH TEAM, DOCTOR, GOOD TO SEE YOU AGAIN. WHAT'S THE BIG TAKEAWAY FROM WHAT YOU'VE DONE THERE? >> Reporter: THANKS FOR HAVING ME BACK. WHAT IS REALLY EXCITING ABOUT THIS DRUG IS IT'S AVAILABLE, SO IN AND OUT PATIENT SETTINGS. PEOPLE DON'T NEED TO BE ISOLATED. WE HOPE THIS COULD BE AVAILABLE TO MORE PEOPLE IN A MUCH SIMPLER MANNER ONCE THEY MAKE IT THROUGH TRIALS. >> WITH ALL THE INTEREST IN THE MUTATING VARIANTS, DOES THIS DRUG SHOW PROMISING SIGNS IN THAT REGARD? >> SO WE HAVEN'T TESTED IT, BUT THE MECHANISM OF ACTION SHOULD HAVE NOTHING TO DO WITH THOSE VARIANTS AT ALL. THIS DRUG TARGETS THE WAY THE VIRUS REPLICATES ITSELF. THOSE SPECIFIC PROTEINS, COPYING IT, THE VARIANTS HAVE TO DO WITH THE SPIKE PROTEIN, WHICH HELPS THE VIRUS FINE TO AND INFECT OURSELVES, SO IT SHOULD NOT HAVE ANY ISSUES WITH THE NOVEL VARIANTS AT ALL. >> JUST AMAZED AT ALL THE RESEARCH AND THE BREAKTHROUGH THERE. HOW LONG HAVE YOU BEEN WORKING ON THIS SPECIFIC DRUG? >> AND SO THIS SPECIFIC DRUG WE STARTED TO WORK WITH BEFORE SARS 2 EVEN BECAME KNOWN TO US. WE HAD TESTED IT WITH OTHERS. AND WHEN COV-2 CAME OUT, WE HAD TO DEVELOP MORE. IT WORKS INCREDIBLY WELL. >> ALL RIGHT, THE LAST QUESTION, THE OBVIOUS ONE, WHEN MIGHT WE SEE THIS ON THE MARKET? WHEN MIGHT IT BE AVAILABLE FOR ME AND EVERYONE WATCHING? >> I WOULD HOPE SOME TIME LATER THIS YEAR IT'S BEEN IN PHASE TWO TRIALS AND NOW IT'S IN COMBINED PHASE TWO/THREE TRIALS, SO IT'S BEING PUSHED FORWARD. HOPEFULLY IT COULD BE ONE OF THOSE, YOU KNOW, EARLY DRUGS THAT BECOMES AVAILABLE TO PEOPLE PRETTY QUICKLY. >> DOCTOR, ALWAYS AMAZING TO TALK WITH YOU AND YOUR TEAM. KEEP UP THE GREAT WORK.

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Experimental COVID-19 drug could be given orally, meaning it would be easier for more people to take

UNC researcher Lisa Gralinski

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I'm meteorologist K Campbell in the severe weather center. It's feeling like summer again. On Thursday, high temperatures reach the upper eighties and we could come awfully close to 90 in Fayetteville. It's possible. Fayetteville sees the 1st 90 degree day of the year. The average first day in the nineties in Fayetteville is, is May 3rd and May twelveth here in the triangle. 87 in the triangle and 85 in rocks, a lot more sunshine in the forecast tomorrow. Those clouds that we saw, they're going to be clearing out overnight. So get some fresh air, enjoy it while you can. We're not going to see these warm days every day for our seven day. We'll wake up to temperatures in the low sixties warming up to 80 degrees by noon and upper eighties for highs during the afternoon. We've got the sunshine tomorrow, but a lot of us could really use the rain, especially anybody who's starting with their gardening, our rainfall for the month of April 66 inches. So that's more than an inch below normal. I would recommend to keep watering your gardens. We do have some opportunities for rain, but none of these rounds look like a widespread soaking rain. I would go ahead and keep watering. We've got a 40% chance of storms on the way. Friday and Friday, we need to keep an eye on the potential for a severe storm. Tonight. We're seeing showers dissipate as they move closer to us. And that trend should continue. We dry out throughout the day tomorrow with the sunshine and then here comes Friday's front in the morning, we'll see some rain in the mountains kind of falling apart. But as this front gets closer to us during the afternoon, as we're heating up, we'll have a more energized atmosphere and this should create some lift to generate some scattered storms throughout the afternoon and evening. It's about a 40% chance that you would see one at your house. The issue is pretty much anywhere in our viewing area. There could be a severe storm. That's why there's level one out of five threat for severe storms, Friday. The threats, damaging wind gusts and hail your seven day forecast shows some big changes are on the way for the weekend. We are cooling down, especially on Sunday, just 68 for the high falling into the 40 Sunday night into Monday morning, Monday, mostly cloudy, some lingering sprinkles possible. And then next week, temperatures are right back in the mid seventies, which is pretty much on par with where we should be this time of year

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Good evening. I'm Gail her. Welcome to tonight's drawing for Wednesday, April 17th, 2024. Well, let's get start tonight with our Carolina pick three. Our first winning numbers are two. Our second number is nine and the third number tonight is six and our pick three. Fireball number is an eight. Joining me for tonight's show is the auditor from mcconnell and Jones L LP. Now lets move of the Carolina pick four. Good luck. Everyone who's that first number. It's a three. Our second pick four. Number is one, third, one is one again and our fourth pick four number is a nine and our pick for fireball number is a six. Well, turning now to the Carolina cash five. If no one was the top prize tonight, tomorrow's top prize is estimated at $191,000. Good luck. Everyone is that first winning cash five number. It's 33. Our second number is an eight third number. Tonight is 10. Our fourth number is 22 and the final number in our cash five this evening, 41 the North Carolina education lottery has contributed over $10 billion to education. Get your winning numbers right here every night at your exclusive station for the North Carolina Education lottery. Thanks for playing. Have a great night.

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Is powerball. Good evening, everyone. I'm Randy Trainer. Tonight. We have our life changing jackpot. It's estimated to be $80.7 million to get your tickets ready. Here. Come, tonight's winning numbers. Let's start things off this evening with the number 24. Right after that America. We have the number 54 and congratulations to Lisa Hayes from Illinois. She won $2 million playing powerball. All right, the rest of your winning number is 4447. And let's round it out tonight with the number 29 and tonight's win powerball number that's gonna be two and your power play multiplier is two. Let's take a look at tonight's winning numbers. Remember there are multiple ways to win. Good luck, everyone. We'll see you back here on Saturday night. It's time to play America's favorite.

Powerball Drawing

A crash has shut down all but one lane of Interstate 540 westbound near Buffaloe Road in Raleigh. Sky 5 is over the scene

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Daytime Pick 3 and Pick 4 drawings are held at 3 p.m. daily. They can be seen as live or on-demand video.

Hey there. Good afternoon. I'm Noah Klein. Welcome to this afternoon's draws for Wednesday, April 17th, 2024. Let's get started here with Carolina pick three. That first pick three number is eight, second number is nine. Third number is eight pick 35. Ball number is one. Joining me for this afternoon's drawings are auditor from mcconnell and Jones L LP. Let's move to the Carolina pick four. That first pick four. Number is nine eight third number 64. Number is five and a pick for firewall number is five. The North Carolina Education lottery contributed over $10 billion to educate occasion. Thank you for your support. You get your winning numbers each day at 3 p.m. and again at 11:22 p.m. right here on your exclusive station for the North Carolina Education Lottery.

Daytime Pick 3 and Pick 4 Drawing

Tuesday and Friday Mega Millions Drawing.

>> ACROSS AMERICA WITH MEGA JACKPOTS, IT'S MEGA MILLIONS. HELLO, MAYOR COMES ON CODE IS TUESDAY. APRIL 16TH AND TONIGHT'S MEGA MILLIONS JACKPOT IS AN ESTIMATED A NEW TIES. 148 MILLION DOLLARS. >> DUE TO TECHNICAL DIFFICULTIES. TONIGHT'S DRAWING HAS BEEN TEMPORARILY HALTED. ONCE THE MALFUNCTION IS CORRECTED, THE DRAWING WILL CONTINUE UNDER THE SUPERVISION OF THE AUDITOR. WE SAY TO THE STATION FOR ALL WINNING NUMBERS. >> SPOTTY SHOWERS AND THUNDERSTORMS POPPING UP HOW

Mega Millions Drawing

Fans of the NC State Wolfpack's men's and women's basketball teams are celebrating the teams' run to the Final Four on Monday night on Hillsborough Street at the Memorial Belltower. NC State Chancellor Randy Woodson, Athletics Director Boo Corrigan and Raleigh Mayor Mary-Ann Baldwin are expected to speak Monday night at the event.

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