Victoria T'nya-Ann Carter, 20, of Raleigh, was riding in the back seat on the right. She was pronounced dead at the scene.
The driver, Kamil Shaunay Arrington, 20, of Nash County, and two other passengers, Taylor Nicole King, 19, of Greenville, and Briana Latrice Gather, 20, of Kernersville, were taken to Pitt County Memorial Hospital.
Gather died on Sunday. King was in fair condition. A condition update for Arrington was not available.
Police said Arrington's car ran off the road at Greenville Boulevard and Rosewood Drive and hit a tree just before dawn Saturday. They said that it does not appear alcohol played a role in the wreck.
Carter and the other women were members of the pledge class for Delta Sigma Theta at East Carolina, the Associated Press reported. Carter also was a member of the school's Black Student Union.