99-year-old man gets COVID antibody treatment, celebrates 100th birthday

And on Zoom, chatting with his kids and grandkids.

Littleton, who lives in Creedmoor, tested positive for COVID on Jan 7.

Then, his son and daughter-in-law became infected, too.

Because all three are considered high-risk, they all received a monoclonal antibody infusion at WakeMed.

"When I got it, I was almost better. I got better pretty quickly, considering what other people are going through," said his son Thomas.

The FDA describes monoclonal antibodies as laboratory-made proteins that mimic the immune system’s ability to fight off dangerous viruses.

This cocktail is specifically directed against the coronavirus.

After his infusion, Littleton stayed at WakeMed for a few days -- his oxygen level had dropped, and he had trouble breathing.

He went back to the hospital a second time because of breathing trouble, but he never went on a ventilator.

After three weeks, he was all cleared of COVID.

For his birthday, however, he is at UNC Rex Hospital, after his heart went into atrial fibrillation.

Fortunately, that is also now under control, and he could be going home soon.

"It's very emotional. Very emotional, especially when I'm talking to the nurses in the hospital about his progress, when they tell me how he's doing. It's just amazing how good they are to him," said Thomas.

They don't know how much of a difference the monoclonal antibody treatment made.

But they know this much: Isaac Littleton made it to his 100th birthday.