The bear was struck by a Chevrolet Tahoe between mile markers 448 and 449 in Spring Hope around 2:45 a.m., according to the Nash County Sheriff's Office. The bear died instantly, and no one in the Tahoe was injured.
A State Department of Transportation crew arrived in the early afternoon to take away the bear carcass.
The Triangle saw a rash of bear sightings in May.
State biologists say that young bears are always on the move this time of year, looking for food and mates. Male bears have ranges of about 70 square miles and can travel 10 to 12 miles a day.
Mother bears kick young males out of the den in the late spring to avoid inbreeding, forcing them to find their own range.
Wildlife officials say that anyone who sees a bear should leave it alone and call authorities to report it.
People in areas where bears have been seen should be careful about not leaving their trash out overnight. Instead, put the trash out the morning of the day it's picked up.