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No more drug-resistant H1N1 found at Duke

Posted December 1, 2009

— Extensive testing has found no more cases of drug-resistant H1N1 flu at Duke University Hospital, officials said Tuesday.

The hospital reported on Nov. 20 that two men and two women had contracted a strain of the virus that was resistant to the drug Tamiflu, one of two medicines used to fight H1N1. Both men and one woman died.

The patients had been treated in an isolated unit of the hospital in the six weeks prior to the Nov. 20 announcement, and all had underlying compromised immune systems and other complex medical conditions at the time, officials said.

The U.S. Centers for Disease Control and Prevention and the state Division of Public Health worked with Duke Hospital to test all other patients in the isolated unit several times in recent days. Other people being treated for H1N1 at the hospital also were tested.

"Much work is still being done to better understand the nature of the four cases that were reported previously," Dr. Daniel Sexton, an infectious disease specialist and director of the Duke Infection Control Outreach Network, said in a statement.

About 52 Tamiflu-resistant cases have been reported in the world since April, including 15 in the U.S. Last summer, health officials said two people in western North Carolina also had a drug-resistant form of the virus.

Tamiflu is still the most effective treatment for the H1N1 virus, and a vaccination is the best prevention for contracting the virus, health officials said. No resistance has been found to Relenza, the other drug approved to treat H1N1, they said.

Since the H1N1 pandemic began, 58 people in North Carolina have died as a result of the virus, health officials said.


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  • wattsun Dec 4, 2009

    Orange RN ,am I spreading misinformation? No.
    Posted a Very Plausible theory . Yes
    I am well informed on this subject.
    You may be the one that needs to Dig deeper.

    Ask yourself why would they take the chance of passing out a live virus in the form of a nasal vaccine knowing the possible consequences?

    Viruses shed and mutate and this is what we are seeing now.

  • sssh.. whisper Dec 2, 2009

    wattsun- More than likely (because of underlying health problems) the patients had the shot. Generally, the mist was given to those individuals who were deemed "healthy" (no prior health problems and not pregnant)

  • Orange RN Dec 1, 2009

    wattsun, stop spreading misinformation. The pan H1N1 vaccine remains well-matched to the circulating pan H1N1 virus at this time.

    Flu-Mist has nothing to do with the D225G mutation which was detected before vaccination started.

    Ukraine politicians used the fact of their pan H1N1 outbreak and fed the news media frenzy for political purposes.

    Dig deeper for the truth, it is easy to find lies.

  • Nunya123 Dec 1, 2009

    Wow, you can tell by the number of posts here that no one really cares. Most are tired of the hype.

  • wattsun Dec 1, 2009

    The Good News has been that though this mutation is virulent it seems to be Really hard to catch.
    I WISH someone in the media would confirm or deny that these 3 people had the H1N1 vaccine or Flu Mist prior ?
    This is the Key.
    I would almost bet the house they were vaccinated or around someone who had been recently vaccinated with Flu Mist.
    The artcle is also not accurate saying vaccination will prevent you catching "H1N1-D225G" this is totally unproven.
    In the Ukraine cases of the mutation:
    One sample of the Ukraine flu virus has been classed as a low reactor to the H1N1 vaccine. If this mutation spreads, it could result in infection for people who have been vaccinated against the swine flu. Other mutations that have been identified include Tamiflu resistance and complete destruction of the lungs. Vaccines are created to respond to each different type of virus, and must be adapted if the virus changes too much from the original.