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Published: 2010-08-12 11:33:00
Updated: 2010-08-12 18:58:30

Pharmacist: Brand has 'nothing to do' with quality of medication


pain reliever
pain reliever
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Some parents may have noticed a lot of familiar child's pain relievers are hard to find. Over the past six to eight months manufacturers of Tylenol and Motrin products have voluntarily pulled most of the medications from shelves due to quality-control issues.

There are still options available that are cheaper than and just as good as the brand names.

Generic store brands are plentiful, but Compounding Pharmacist Rikesh Patel with Brier Creek Pharmacy says some people think cheaper price means cheaper quality.

"I guess you're paying for the brand and the name most of the time. That has nothing to do with the quality, just because it's an inexpensive medication,” Patel said.

Some child's Motrin and Tylenol products are still available because they were made at different facilities than other recalled products. Some of those brand name products, even with the higher price, had concentration issues.

“Some medications were stronger than what was recorded on the label. Some were actually weaker,” Patel said.

Even if generic brands were in short supply, Patel is a compounding pharmacist who's specially trained to formulate medications for customers, even pediatric pain relievers.

“We can make them taste better or dye-free in a lot of cases. A lot of kids are allergic to certain dyes and things like that,” Patel said.

When parents shop for over-the-counter medications, the decision has become more complicated. There have been several dosage changes over the past year or two because many parents gave medications to their infant that weren't intended for them, so seek out your pharmacist.

“And I'd encourage parents not to just buy off the shelf. I'd encourage them to come out and at least have a conversation with the pharmacist any time their child is sick,” Patel said.

Parents should be careful using multi-symptom pain relievers, which often contain medications for symptoms their child may not have. Your pharmacist can recommend the best combination of medications for you or your child.


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Quality issues are investigated by the FDA and all companies must comply with those regulations. The FDA regularly inspects facilities to insure that companies are in compliance and those who are not are dealt with swiftly and in some cases harshly. Some consequences involve shutting down facilities until they return to compliance.

Generic products must contain the exact label claim as the "brand" product. They must also contain the same inactive ingredients, but most companies use reverse engineering to determine the amounts since the "brand" doesn't willingly disclose this information. The generic product must pass bioequivalence testing before it is approved by the FDA. This means that the generic performs, within reasonable tolerance limits, just like the “brand” name product. We know from personal experience that sometimes the brand works or makes us feel differently than when we take a generic product. Mostly, I think this based on the individual since large percentages are not affected differently. You should never take a product other than what is prescribed. I would never “take an extra pill” unless a physician prescribes it. A lot of “brand” manufacturers are producing “generic” versions of their product to compete against the generic companies to maintain market share after patents

As someone who has worked for big pharma and generic pharmaceutical companies in R&D, some posters on here are posting misconceptions.

All inert and active raw materials, no matter where they are manufactured, are tested before they are put into a final product. While I wouldn't want to take anything manufactured in China or India, U.S. products are pretty safe if you consider the sheer number of units produced. The unscrupulous products manufactured in foreign countries are distributed in those countries and don't make it into the U.S. supply. Any facility that produced any raw material or final product, domestic or foreign, must be inspected by the FDA to insure that the facility is compliant with current good manufacturing practices (cGMP).

Most ingredients of our important drugs are made in China The New York Times has been running a report on the iffy controls in Chinese pharma factories. I would urge people to read these reports as China does not usually let our FDA inspect these manufacturers.

I thought that by law, generics must contain the same concentration of the active ingredient(s) of the name brand. The difference in price doesn't (or shouldn't) come from less active ingredient, but the fact that the generic brand does not have to make up all of the costs spent on researching the drug the way the name-brand did. Is this not true?

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